API & Fine Pharmaceutical Manufacturer in India
Magnesium Pidolate
  • Product Name:

    Magnesium Pidolate

  • Molecular Formula:
    C10H12MgN2O6
  • Molecular Weight:
    280.52 g/mol
  • CAS No.:
    135701-98-3
  • CID Code:
    18601084
  • Shelf Life:
    3 years - 20°C powder
  • Pharmaceutical Grade:
    European Pharmacopoeia (EP)
  • ATC Code (WHO)
    A12CC08
  • ChemSpider ID
    8014340
  • UNII No.
    V5PC588N7G

USP of Magnesium Pidolate

  • High bioavailability for better absorption
  • Low solubility for reduced digestive side effects
  • Neutral pH for minimal stomach irritation
  • Improved magnesium status for overall health
  • Potential for better sleep quality
  • Possible benefits for bone health

IUPAC Names of Magnesium Pidolate

magnesium;(2S)-5-oxopyrrolidine-2-carboxylate

Synonyms of Magnesium Pidolate

  • Magnesium pidolate
  • Pidolic acid magnesium salt (2:1)
  • magnesium pyroglutamate
  • 135701-98-3
  • magnesium;(2S)-5-oxopyrrolidine-2-carboxylate
  • Bis(5-oxo-L-prolinato-N1,O2)magnesium
  • V5PC588N7G
  • L-Proline, 5-oxo-, magnesium salt (2:1)
  • UNII-V5PC588N7G
  • Magnesium, bis(5-oxo-L-prolinato-N1,O2)-, (T-4)-
  • 5-Oxo-L-proline magnesium salt (2:1)

MSDS of Magnesium Pidolate

Download MSDS PDF
First Aid Measures
  • Eye Contact: Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at least 15 minutes. Get medical attention if irritation occurs.
  • Skin Contact: Wash with soap and water. Cover the irritated skin with an emollient. Get medical attention if irritation develops.
  • Ingestion: Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. If large quantities of this material are swallowed, call a physician immediately. Loosen tight clothing such as a collar, tie, belt or waistband.
  • Inhalation: If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention.
Fire-Fighting Measures
  • Flammability of the Product: May be combustible at high temperature.
  • Auto-Ignition Temperature: Not available.
  • Flash Points: Not available.
  • Flammable Limits: These products are carbon oxides (CO, CO2), nitrogen oxides (NO, NO2…). Some metallic oxides.
  • Products of Combustion: Slightly flammable to flammable in presence of heat. Non-flammable in presence of shocks.
  • Fire Hazards in Presence of Various Substances: Slightly explosive in presence of open flames and sparks. Non-explosive in presence of shocks.
  • Fire Fighting Media and Instructions:
    SMALL FIRE:
    Use DRY chemical powder.
    LARGE FIRE: Use water spray, fog or foam. Do not use water jet.
  • Special Remarks on Fire Hazards: As with most organic solids, fire is possible at elevated temperatures
  • Special Remarks on Explosion Hazards: Fine dust dispersed in air in sufficient concentrations, and in the presences of an ignition source is a potential dust explosion hazard.
Exposure Controls / Personal Protection
  • Eyes: Wear appropriate protective eyeglass or chemical safety goggles. Make sure that there is an eyewash facility in your vicinity.
  • Skin: Wear impervious gloves and protective clothing.
  • Respiratory: Use a NIOSH approved respirator when exposure limits are exceeded or if irritation or other symptoms are experienced.
  • Exposure Limits: Consult local authorities for acceptable exposure limits.
Physical and Chemical Properties
  • Appearance Form: Amorphous hygroscopic
    Powder
  • Color: White or almost white
  • Odour: No data available
  • pH of 10 % w/v aqueous solution: 5.50 – 7.00
  • Melting point/freezing point: No data available
  • Initial boiling point and boiling range: No data available
  • Sublimation Temperature: No data available
  • Density: No data available
  • Vapour pressure: No data available
  • Vapour density: No data available
  • Refractive Index: No data available
  • Water solubility: Freely soluble in water.
  • Decomposition temperature: No data available
  • Viscosity: No data available
  • Other safety information: No data available
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Description of Magnesium Pidolate

Magnesium pidolate is a white, odorless powder with a slightly bitter taste. It’s known for its good dispersibility in water, making it a well-absorbed form of magnesium. Unlike some other magnesium compounds, magnesium pidolate exhibits low hygroscopicity, meaning it resists absorbing moisture from the air.

This translates to a stable powder that doesn’t clump easily and has a dry, fine texture. Chemically, magnesium pidolate is a coordination complex. It combines magnesium with pidolic acid, a molecule derived from the amino acid L-pidoleucine. This unique structure is thought to contribute to its enhanced bioavailability compared to other magnesium forms.

As a leading API manufacturer, WBCIL prioritizes strict CGMP and ISO quality control measures throughout the production process. The prolonged experience from 1962 ensures consistent potency, purity, and safety in every dose of WBCIL’s Magnesium pidolate.

Application of Magnesium Pidolate

  • Magnesium Supplementation: It is used to treat and prevent magnesium deficiency, which can occur in conditions such as gastrointestinal disorders, renal dysfunction, or chronic alcoholism.
  • Stress Relief: Magnesium pidolate is believed to play a role in stress management as magnesium is known to support the nervous system.
  • Muscle Function: It helps in the normal functioning of muscles, providing relief from cramps, spasms, and aches.
  • Cardiovascular Health: Magnesium is vital for heart health, and magnesium pidolate can be used to support cardiovascular function.
  • Bone Health: It contributes to the maintenance of normal bone density, which is essential in the prevention and treatment of osteoporosis.
  • Metabolic Regulation: Magnesium is a cofactor in many enzymatic reactions in the body, including those involved in energy metabolism.
  • Neurological Function: It has roles in neurotransmitter release and modulation, and thus may be used in the management of neurological conditions.
  • Pregnancy and Lactation: Magnesium pidolate may be used to meet the increased magnesium requirements during pregnancy and lactation.
  • Paediatric Applications: It can be formulated for paediatric use to address magnesium deficiencies or metabolic needs in children.
  • Psychological Functions: Magnesium is involved in psychological functions, so magnesium pidolate can be used to support cognitive and mental health.
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