Relevant identified uses of the substance or mixture and uses advised against: Laboratory chemicals, Manufacture of substances
Uses advised against: Do not use for private purposes (household). Food, drink and animal feeding stuffs.
First Aid Measures
Inhalation: If Sodium Butyrate is inhaled, remove to fresh air. If breathing is difficult, give oxygen. Get medical attention.
Ingestion: Give large amounts of water to drink. Never give anything by mouth to an unconscious person. Get medical attention.
Skin Contact: In case of contact, immediately flush skin with plenty of water. Cover the irritated skin with an emollient. Remove contaminated clothing and shoes. Cold water may be used. Wash clothing & Shoes before reuse. Get medical attention.
Eye Contact: Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at least 15 minutes. Cold water may be used. Get medical attention.
Fire-Fighting Measures
Fire: Sodium Butyrate is not expected to be a fire hazard.
Explosion: No information found.
Fire Extinguishing Media: Use any means suitable for extinguishing surrounding fire.
Special Information: In the event of a fire, wear full protective clothing and self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode.
Handling and Storage
Keep Sodium Butyrate in a tightly closed container, stored in a cool, dry, ventilated area. Protect against physical damage. Containers of Sodium Butyrate may be hazardous when empty since they retain product residues (dust, solids); observe all warnings and precautions listed for the product.
Physical and Chemical Properties
Appearance Form: Free flowing powder, with occasional friable lump.
Butyrate plays an important role in digestive system by providing the main energy source for colon cells; it meets about 70% of their energy needs. Butyrate can provide other health benefits as well, including supporting the immune system, reducing inflammation, and preventing diseases like cancer. Sodium Butyrate is the sodium salt of butyrate with potential antineoplastic activity.
Application of Sodium Butyrate Food/USP
In the Food Industry:
Flavor Enhancer: Used as a flavoring agent due to its buttery taste, often in dairy products and baked goods.
Food Preservative: Acts as a preservative by inhibiting the growth of mold and some bacteria in food products.
Animal Feed Supplement: Improves gut health and the nutritional status of livestock, leading to better growth and overall health of the animals.
Dietary Supplement: Incorporated into dietary supplements for its potential health benefits, including gut health and anti-inflammatory properties.
In Pharmaceuticals (USP Grade):
Colon Health: Used in the treatment of various gastrointestinal disorders, including irritable bowel syndrome (IBS) and inflammatory bowel diseases (IBD) like Crohn’s disease and ulcerative colitis.
Cancer Therapy: Investigated for its potential anti-cancer properties, particularly in colorectal cancer.
Neurological Disorders: Shows promise in the treatment of certain neurological disorders due to its effects on gut-brain axis and anti-inflammatory properties.
Gastrointestinal Drug Formulations: Used in specific drug formulations to improve colon health and treat gastrointestinal disorders.
Epigenetic Effects: Has been studied for its role in influencing gene expression through epigenetic mechanisms, which could have various therapeutic applications.
Anti-Inflammatory Properties: Utilized for its anti-inflammatory effects in various conditions, potentially including skin disorders.
Metabolic Health: Investigated for its potential benefits in metabolic syndromes, including obesity and diabetes.
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