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Product Name:
Magnesium Orotate
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Molecular Formula:
C10H6MgN4O8.xH2O
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Molecular Weight:
370.51 g/mol
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CAS No.:
1381769-22-7
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CID Code:
3036905
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Shelf Life:
3 years - 20°C powder
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Pharmaceutical Grade:
Non-Pharmacopeial
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ATC Code (WHO)
A12CC09
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DrugBank ID
DB13786
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ChemSpider ID
2300801
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UNII No.
GI96W46M5A
- USP
- IUPAC Names
- Synonyms
- MSDS
USP of Magnesium Orotate
- The binding of magnesium to orotic acid improves absorption.
- selectively delivered to mitochondria.
- cause less digestive issues.
- Orotic acid is involved in the synthesis of pyrimidines, essential components of DNA and RNA. By providing magnesium, a cofactor in these processes, magnesium orotate could potentially support nucleic acid synthesis and cellular growth.
- Supports heart health.
IUPAC Names of Magnesium Orotate
magnesium;2,4-dioxo-1H-pyrimidine-6-carboxylate
Synonyms of Magnesium Orotate
- Magnesium orotate
- 34717-03-8
- Orotate magnesium
- magnesium;2,4-dioxo-1H-pyrimidine-6-carboxylate
- Orotic acid, magnesium salt
- Magnesium,bis(1,2,3,6-tetrahydro-2,6-dioxo-4-pyrimidinecarboxylato-kN3,kO4)-, (T-4)-
- GI96W46M5A
- Magnesium bis(2,6-dioxo-1,2,3,6-tetrahydro-4-pyrimidinecarboxylate)
- Bis(1,2,3,6-tetrahydro-2,6-dioxopyrimidine-4-carboxylato-N3,O4)magnesium
- UNII-GI96W46M5A
MSDS of Magnesium Orotate
Download MSDS PDF- Eye Contact: Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at least 15 minutes. Get medical attention if irritation occurs.
- Skin Contact: Wash with soap and water. Cover the irritated skin with an emollient. Get medical attention if irritation develops.
- Ingestion: Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. If large quantities of this material are swallowed, call a physician immediately. Loosen tight clothing such as a collar, tie, belt or waistband.
- Inhalation: If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention.
- Flammability of the Product: May be combustible at high temperature.
- Auto-Ignition Temperature: Not available.
- Flash Points: Not available.
- Flammable Limits: These products are carbon oxides (CO, CO2), nitrogen oxides (NO, NO2…). Some metallic oxides.
- Products of Combustion: Slightly flammable to flammable in presence of heat. Non-flammable in presence of shocks.
- Fire Hazards in Presence of Various Substances: Slightly explosive in presence of open flames and sparks. Non-explosive in presence of shocks.
- Fire Fighting Media and Instructions:
SMALL FIRE: Use DRY chemical powder.
LARGE FIRE: Use water spray, fog or foam. Do not use water jet. - Special Remarks on Fire Hazards: As with most organic solids, fire is possible at elevated temperatures
- Special Remarks on Explosion Hazards: Fine dust dispersed in air in sufficient concentrations, and in the presences of an ignition source is a potential dust explosion hazard.
- Eyes: Wear appropriate protective eyeglass or chemical safety goggles. Make sure that there is an eyewash facility in your vicinity.
- Skin: Wear impervious gloves and protective clothing.
- Respiratory: Use a NIOSH approved respirator when exposure limits are exceeded or if irritation or other symptoms are experienced.
- Exposure Limits: Consult local authorities for acceptable exposure limits.
- Appearance Form: Powder
- Color: White to off-white
- Odour: No data available
- pH of 2 % w/v aqueous suspension: 6.0 – 7.5
- Melting point/freezing point: No data available
- Initial boiling point and boiling range: No data available
- Sublimation Temperature: No data available
- Density: No data available
- Vapour pressure: No data available
- Vapour density: No data available
- Refractive Index: No data available
- Water solubility: Slightly soluble in water.
- Decomposition temperature: No data available
- Viscosity: No data available
- Other safety information: No data available
Description of Magnesium Orotate
Magnesium orotate, a mineral supplement for magnesium deficiency, boasts a unique structure. It combines magnesium (Mg²⁺) with orotic acid (C₅H₄N₂O₄⁻) molecules. While information on its color and texture is scarce, magnesium orotate is likely a white, odorless powder due to its ionic nature.
Interestingly, despite containing orotic acid (water-soluble), magnesium orotate itself is reported to have poor water solubility. This could influence its absorption rate in the body. On the other hand, its chelated structure, where magnesium is bound within a ring of atoms, might enhance its bioavailability compared to other magnesium forms.
As a leading API manufacturer, WBCIL prioritizes strict CGMP and ISO quality control measures throughout the production process. The prolonged experience from 1962 ensures consistent potency, purity, and safety in every dose of WBCIL’s Magnesium orotate.
Application of Magnesium Orotate
Enhanced Magnesium Absorption
Improved Bioavailability: The binding of magnesium to orotic acid enhances its absorption, making magnesium orotate an efficient choice for individuals needing to increase their magnesium levels. The orotic acid helps deliver magnesium more effectively to the body’s cells, particularly the mitochondria.
Selective Delivery to Mitochondria
Targeted Cellular Support: Magnesium orotate is selectively delivered to mitochondria, the energy powerhouses of the cell. This targeted delivery supports cellular energy production and can be beneficial for overall cellular function, including growth and repair.
Reduced Digestive Issues
Gentle on Digestion: Magnesium orotate is less likely to cause common gastrointestinal issues, such as diarrhea or stomach upset, compared to other magnesium forms. This makes it suitable for individuals with sensitive digestive systems who require magnesium supplementation.
Nucleic Acid Synthesis and Cellular Growth
Support for DNA and RNA Production: Orotic acid plays a role in the synthesis of pyrimidines, which are essential components of DNA and RNA. Magnesium orotate provides magnesium, a cofactor in these processes, potentially supporting nucleic acid synthesis, promoting healthy cellular growth and repair, and enhancing overall cellular function.
Heart Health Support
Cardiovascular Benefits: Magnesium orotate is particularly beneficial for heart health. It supports the proper function of the heart muscle and may improve outcomes in individuals with cardiovascular issues, such as heart arrhythmias or angina, by supporting energy production in heart cells and improving overall heart function.
