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Zinc Bisglycinate- The Superior Zinc for Optimal Health
Published on: July 17, 2024

Unlocking the Benefits of Zinc Bisglycinate- Superior Bioavailability for Immune and Skin Health

Zinc, an essential mineral often overshadowed by its more glamorous counterparts, is a cornerstone of human health. Involved in over 300 enzymatic reactions, zinc plays a critical role in immune function, skin health, and cognitive function. While various zinc supplements are available, zinc bisglycinate stands out for its superior bioavailability and potential health benefits.

Zinc bisglycinate is a chemical compound characterized by its unique molecular structure and properties. Chemically, it is an amino acid chelated zinc with the formula C4H8N2O4Zn and a molecular weight of approximately 213.5 g/mol. In its structure, a zinc ion is coordinated to two glycine molecules through coordinate covalent bonds, forming a stable chelate complex (Zn(H2NCH2COO)2).

Importance of chelation process

This chelation process enhances zinc’s solubility and bioavailability compared to other zinc salts. Physically, zinc bisglycinate is typically observed as a white to off-white crystalline powder with good water solubility 1. These combined chemical and physical attributes contribute to its superior absorption and utilization within the body.

Zinc, an essential antioxidant, is indispensable for optimal immune function. Zinc supplementation may offer potential benefits in managing acne. Adequate zinc intake has been associated with improved sleep quality in humans. Research suggests a correlation between lower zinc levels and the development of depressive and anxiety symptoms.

Zinc plays a crucial role in inhibiting the enzymatic conversion of testosterone into dihydrotestosterone (DHT), a hormone implicated in various health conditions. Replenishing zinc stores is crucial for optimizing fertility 2.

Early intervention with zinc supplements may potentially alleviate cold symptoms and shorten their duration. Athletes engaged in high-intensity, anaerobic exercise often exhibit elevated zinc levels compared to those involved in other physical activities.

Zinc Bisglycinate Benefits

Uniqueness of  Zinc Bisglycinate

Zinc bisglycinate is a chelated form of zinc, meaning it’s bound to the amino acid glycine. This unique bonding enhances its absorption compared to other zinc forms like zinc oxide or zinc gluconate. When consumed, zinc bisglycinate is more readily absorbed into the bloodstream, maximizing its utilization by the body.

  • Enhanced Bioavailability: Its chelated structure of zinc bisglycinate offers superior absorption and excellent tolerability compared to other zinc forms, surpassing the bioavailability of inorganic zinc salts. For example, Zinc bisglycinate demonstrates superior bioavailability compared to zinc gluconate 3. The chelation process protects zinc from dietary interference, ensuring efficient uptake into the bloodstream.
  • Superior Tolerability: Zinc bisglycinate uses is renowned for its gentle nature on the gastrointestinal tract, reducing the likelihood of digestive disturbances commonly associated with other zinc supplements.
  • Excellent Stability: The chelated form exhibits enhanced stability, safeguarding the zinc ion from degradation during storage and handling. This ensures product consistency and potency.
  • Versatility in Formulation: Its water solubility makes zinc bisglycinate adaptable to various pharmaceutical formulations, accommodating diverse delivery methods.
  • Potential for Drug Delivery: While primarily utilized as a dietary supplement, the chelation properties of zinc bisglycinate offer potential avenues for targeted drug delivery systems.Zinc Chelate Bisglycinate uses

Zinc Bisglycinate Benefits:

  • Immune System Champion: Zinc bisglycinate in pharmacy is a key player in immune function, supporting the production of white blood cells and aiding in the body’s defense against pathogens. Zinc bisglycinate’s superior absorption can enhance these immune-boosting effects.

It plays a vital role in immune health by supporting the production of white blood cells, including natural killer cells, T-lymphocytes, and B-lymphocytes. Beyond immune function, zinc bisglycinate contributes to skin health, wound healing, and the maintenance of healthy vision, particularly in the macula 4. This essential mineral is also involved in regulating testosterone levels, supporting normal growth and development, and maintaining a keen sense of taste and smell.

  • Zinc bisglycinate for skin: Zinc bisglycinate for acne to wound healing, zinc plays a crucial role in maintaining skin integrity. Zinc bisglycinate’s potential to improve zinc levels can contribute to clearer skin and faster wound healing. zinc bisglycinate for hair usage is also common.
  • Wound healing: Looking to accelerate wound healing naturally? Zinc Bisglycinate, a well-absorbed form of zinc, could be a valuable addition to your routine, promoting collagen production for faster recovery 5.
  • Cognitive Powerhouse: Zinc supports brain function, including memory, learning, and mood regulation. While research is ongoing, some studies suggest that adequate zinc intake may benefit cognitive health.
  • Taste and Smell Enhancement: Zinc is essential for maintaining a keen sense of taste and smell. For individuals with impaired senses, zinc supplementation may be beneficial.
  • Potential Benefits for Men’s Health: Zinc plays a role in testosterone production and sperm health. Some research suggests that zinc supplementation may support male fertility.
  • Digestive Health Support: Emerging research suggests that zinc may play a role in maintaining digestive health. While more studies are needed, zinc bisglycinate’s anti-inflammatory properties may offer potential benefits for certain digestive conditions.
  • Weight management: Zinc bisglycinate may support weight management when combined with a balanced diet and regular exercise.

Support your immune system naturally with a combination of Vitamin C and highly-absorbable Zinc Bisglycinate, potentially shortening the duration of the common cold and promoting overall well-being.

Combat fatigue and support healthy red blood cell production with a combination of Ferrous Bisglycinate (iron), Zinc Bisglycinate, and Folic Acid, addressing potential deficiencies and promoting overall well-being.

Other Potential Applications: Beyond the aforementioned areas, zinc bisglycinate may offer benefits for:

  • Eye health: Supporting macular health
  • Taste and smell: Maintaining a keen sense of taste and smell
  • Hair and nail health: Promoting hair and nail growth

Zinc Chelate Bisglycinate

How to Incorporate Zinc Bisglycinate into Your Diet?

While zinc-rich foods like oysters, beef, and pumpkin seeds are excellent sources, supplementation may be necessary to meet optimal zinc levels. Zinc bisglycinate offers a convenient and well-absorbed option 6. Always consult with a healthcare professional before starting any new supplement, especially if you have underlying health conditions or are taking medications.

It’s important to note that while research is promising, individual responses to supplements may vary. Always consult with a healthcare professional before starting any new supplement regimen.

Zinc bisglycinate Dosage:

The recommended daily intake of elemental zinc for adults typically ranges from 15 to 30 milligrams. While zinc bisglycinate is a well-absorbed form of zinc, determining the right dosage for you depends on several factors. The recommended daily allowance (RDA) for adult men is 15mg of elemental zinc, and 12mg for adult women. However, some individuals may require more zinc due to deficiencies, certain medical conditions, or pregnancy. It’s important to consult with a healthcare professional to establish the appropriate dosage for your specific needs, take zinc bisglycinate Precautions and avoid exceeding the tolerable upper intake level (UL) of zinc, which can cause side effects.

Zinc bisglycinate Side effects:

Zinc bisglycinate is generally well-tolerated, but like most supplements, it can cause side effects in some people. These side effects are typically mild and digestive in nature, and may include nausea, stomach cramps, or diarrhea. This can often be mitigated by taking pure zinc bisglycinate with food. Higher doses of zinc bisglycinate indication, exceeding 40mg of elemental zinc daily, can also interfere with copper absorption in the body, potentially leading to a copper deficiency 7. Flavocoxid/citrated zinc bisglycinate may cause adverse reactions in some individuals. Common side effects can include digestive upset such as nausea, diarrhea, and flatulence. In rare cases, more severe reactions like hypertension, skin conditions like psoriasis, jaundice, and liver complications might occur. Additionally, joint swelling has been reported in association with this supplement. It’s essential to consult with a healthcare professional if any concerning symptoms develop.

Conclusion:

Chelated zinc bisglycinate may contribute to overall well-being by supporting immune system function, promoting healthy hair, skin, and nails, enhancing cellular health, aiding in DNA formation, and supporting optimal vision.
It offers a unique advantage in the world of zinc supplements due to its high absorption rate. This means your body can more effectively utilize the zinc for its various functions.
Research suggests potential benefits for wound healing, immune function, and even acne management. However, it’s crucial to remember that zinc bisglycinate, like any supplement, should be taken under proper guidance and at appropriate dosages to avoid side effects. If you’re considering zinc bisglycinate, consult your doctor to determine if it’s right for your individual needs and to ensure safe and effective use.

 

References
1.The Benefits of Zinc Bisglycinate – A Well-Absorbed Super Mineral, THRONE, 2020. https://www.thorne.com/take-5-daily/article/the-benefits-of-zinc-bisglycinate-a-well-absorbed-super-mineral
2. National Center for Biotechnology Information. PubChem Compound Summary for CID 91658954, ZINC bis(glycinate) monohydrate. https://pubchem.ncbi.nlm.nih.gov/compound/ZINC-bis_glycinate_-monohydrate. Accessed July 16, 2024.
3. Toldrá, F. et. al., Opinion on certain bisglycinates as sources of copper, zinc, calcium, magnesium and glycinate nicotinate as source of chromium in foods intended for the general population (including food supplements) and foods for particular nutritional uses[1] – Scientific Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food, 718, 1-26, 2008. https://efsa.onlinelibrary.wiley.com/doi/epdf/10.2903/j.efsa.2008.718
4. What is Zinc bisglycinate? 88HERBS. https://88herbs.com/zinc-bisglycinate/
5. Gandia P, Bour D, Maurette JM, Donazzolo Y, Duchène P, Béjot M, Houin G. A bioavailability study comparing two oral formulations containing zinc (Zn bis-glycinate vs. Zn gluconate) after a single administration to twelve healthy female volunteers. Int J Vitam Nutr Res. 2007 Jul;77(4):243-8. doi: 10.1024/0300-9831.77.4.243. PMID: 18271278. https://pubmed.ncbi.nlm.nih.gov/18271278/
6. What Is Chelated Zinc and What Does It Do? healthline. https://www.healthline.com/health/chelated-zinc#why-we-need-zinc
7. Zinc Supplements: Benefits, Dosage, and Side Effects. healthline. https://www.healthline.com/nutrition/zinc-supplements
Frequently Asked Questions on: Unlocking the Benefits of Zinc Bisglycinate- Superior Bioavailability for Immune and Skin Health
What is zinc bisglycinate and how does it differ from other zinc supplements?

Zinc bisglycinate is a chelated form of zinc, meaning it’s bound to the amino acid glycine. This unique bonding enhances its absorption compared to other forms of zinc like zinc oxide or zinc gluconate, making it more bioavailable and gentle on the digestive system.

What are the key benefits of taking zinc bisglycinate?

Zinc bisglycinate supports immune function, skin health, wound healing, cognitive function, and men’s reproductive health. Its superior bioavailability ensures better absorption and utilization by the body, enhancing these benefits.

How does zinc bisglycinate support the immune system?

Zinc bisglycinate aids in the production of white blood cells, including natural killer cells, T-lymphocytes, and B-lymphocytes, which are crucial for the body’s defense against pathogens. Its superior absorption can enhance these immune-boosting effects.

Can zinc bisglycinate help with acne and skin health?

Yes, zinc plays a crucial role in maintaining skin integrity and promoting wound healing. Zinc bisglycinate’s enhanced absorption can help improve zinc levels, potentially leading to clearer skin and faster wound healing.

Are there any side effects associated with zinc bisglycinate?

Zinc bisglycinate is generally well-tolerated. However, some people may experience mild digestive side effects such as nausea, stomach cramps, or diarrhea. Taking it with food can help mitigate these effects. High doses may interfere with copper absorption, potentially leading to a deficiency.

Can zinc bisglycinate improve cognitive function?

Zinc supports brain function, including memory, learning, and mood regulation. While research is ongoing, some studies suggest that adequate zinc intake may benefit cognitive health.

Is zinc bisglycinate suitable for everyone?

Zinc bisglycinate is generally safe for most people, but it’s important to consult with a healthcare professional before starting supplementation, especially if you have underlying health conditions or are taking other medications.


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