DC Granules
Granules for Direct Compression
DC granules are widely used in pharmaceutical industries for manufacturing tablets and other solid dosage forms. Granulation process involves dry mixing, particle size reduction and dry granulation.
Benefits:
Excellent tableting properties.
Perfect dissolution profile.
Improved flowability.
Decrease dust generation.
Lower costs, faster processing.
| Products | Tapped Density gm/cc (NLT) | Untapped Densitygm/cc (NLT) | Compressibility Index (NMT) | Angle of Repose | Particle Size | Average Tablet Weight (gm) | Elemantal Assay w/w (NLT) | |
|---|---|---|---|---|---|---|---|---|
| #20 Mesh | #80 Mesh | |||||||
| Calcium Citrate Malate | 0.85 | 0.75 | 15 | 28 | 90% | 10% | 1.0 | 20% |
| Calcium Citrate | 0.75 | 0.65 | 15 | 26 | 85% | 15% | 1.5 | 20% |
| Ferrous Sulphate | 1.10 | 1.00 | 20 | 27.5 | 95% | 5% | 0.2 | 28% |
| Iron (III) Hydroxide Polymaltose | 0.80 | 0.65 | 15 | 27.8 | 90% | 10% | 0.6 | 30% |
| Ferrous Fumerate | 0.80 | 0.70 | 20 | 28.5 | 95% | 5% | 0.3 | 28% |
| Ferrous Ascorbate | 0.90 | 0.80 | 20 | 16 | 85% | 15% | 0.6 | 20% |
| Ferric Citrate | 1.00 | 0.90 | 15 | 28 | 80% | 20% | 1.0 | 20% |
| Calcium Citrate Malate | |
|---|---|
| Tapped Density gm/cc (NLT) | 0.85 |
| Untapped Densitygm/cc (NLT) | 0.75 |
| Compressibility Index (NMT) | 15 |
| Angle of Repose | 28 |
| Particle Size #20 Mesh | 90% |
| Particle Size #80 Mesh | 10% |
| Average Tablet Weight (gm) | 1.0 |
| Elemantal Assay w/w (NLT) | 20% |
| Calcium Citrate | |
|---|---|
| Tapped Density gm/cc (NLT) | 0.75 |
| Untapped Densitygm/cc (NLT) | 0.65 |
| Compressibility Index (NMT) | 15 |
| Angle of Repose | 26 |
| Particle Size #20 Mesh | 85% |
| Particle Size #80 Mesh | 15% |
| Average Tablet Weight (gm) | 1.5 |
| Elemantal Assay w/w (NLT) | 20% |
| Ferrous Sulphate | |
|---|---|
| Tapped Density gm/cc (NLT) | 1.10 |
| Untapped Densitygm/cc (NLT) | 1.00 |
| Compressibility Index (NMT) | 20 |
| Angle of Repose | 27.5 |
| Particle Size #20 Mesh | 95% |
| Particle Size #80 Mesh | 5% |
| Average Tablet Weight (gm) | 0.2 |
| Elemantal Assay w/w (NLT) | 28% |
| Iron (III) Hydroxide Polymaltose | |
|---|---|
| Tapped Density gm/cc (NLT) | 0.80 |
| Untapped Densitygm/cc (NLT) | 0.65 |
| Compressibility Index (NMT) | 15 |
| Angle of Repose | 27.8 |
| Particle Size #20 Mesh | 90% |
| Particle Size #80 Mesh | 10% |
| Average Tablet Weight (gm) | 0.6 |
| Elemantal Assay w/w (NLT) | 30% |
| Ferrous Fumerate | |
|---|---|
| Tapped Density gm/cc (NLT) | 0.80 |
| Untapped Densitygm/cc (NLT) | 0.70 |
| Compressibility Index (NMT) | 20 |
| Angle of Repose | 28.5 |
| Particle Size #20 Mesh | 95% |
| Particle Size #80 Mesh | 5% |
| Average Tablet Weight (gm) | 0.3 |
| Elemantal Assay w/w (NLT) | 28% |
| Ferrous Ascorbate | |
|---|---|
| Tapped Density gm/cc (NLT) | 0.90 |
| Untapped Densitygm/cc (NLT) | 0.80 |
| Compressibility Index (NMT) | 20 |
| Angle of Repose | 16 |
| Particle Size #20 Mesh | 85% |
| Particle Size #80 Mesh | 15% |
| Average Tablet Weight (gm) | 0.6 |
| Elemantal Assay w/w (NLT) | 20% |
| Ferric Citrate | |
|---|---|
| Tapped Density gm/cc (NLT) | 1.00 |
| Untapped Densitygm/cc (NLT) | 0.90 |
| Compressibility Index (NMT) | 15 |
| Angle of Repose | 28 |
| Particle Size #20 Mesh | 80% |
| Particle Size #80 Mesh | 20% |
| Average Tablet Weight (gm) | 1.0 |
| Elemantal Assay w/w (NLT) | 20% |
The granulation in the pharmaceutical industry, as utilized by West Bengal Chemical Industries Limited, involves techniques such as dry mixing, particle size reduction, and dry granulation. This method is key for producing DC granules, which are essential for manufacturing tablets and other solid dosage forms. Granulation enhances product quality by improving tableting properties, dissolution profiles, flow ability, and reducing dust generation, all while lowering production costs and accelerating processing times.
DC granules, utilized extensively by West Bengal Chemical Industries Limited in the pharmaceutical sector, are crucial for crafting tablets and other solid dosage forms. This process underscores the importance of granulation in the pharmaceutical industry, demonstrating WBCIL’s commitment to leveraging advanced manufacturing techniques for superior product quality.
DC granule (Direct Compression granule) is a type of granulated powder specifically designed for direct compression in tablet manufacturing without the need for additional processing steps.
DC grade refers to raw materials or excipients that are suitable for direct compression in tablet formulation, ensuring consistency, flowability, and compressibility.
Major manufacturers of DC granules in India include our company West Bengal chemical Industries Limited.
Granules are used in the pharmaceutical industry for tablet production, improving the flow and compression properties of powders to ensure uniformity and stability in the final product.
The four types of granules commonly referred to in pharmaceuticals are:
- Wet granulation
- Dry granulation
- Direct compression granules
- Effervescent granules
The colors of DC granules can vary depending on the specific formulation and excipients used, but they are typically white or off-white.
DC grade raw material refers to substances that are pre-processed to be directly compressible, making them suitable for immediate use in tablet manufacturing without further granulation.
The full form of DC granules is Direct Compression granules.
Yes! WBCIL’s DC granules are approved.