L – Methyl Folate


L Methyl folate is widely used in pharmaceutical drugs for treating Megaloblastic Anemia, depression, and renal impairment. Also treats folate deficiency in patients with major depressive disorder. It acts as anti-oxidants therefore used in supplements. MTHF & USP grade available.

Product Brief Description

General Information

Molecular Formula – C20H23CaN7O6

Molecular Weight – 497.5 gm/mol

CAS No – 151533-22-1

Shelf Life – 36 months

Storage Condition – Keep Well Closed, protected against light, dry and at room temperature


1. Description White to yellow color to light brown powder
2. Solubility Sparingly soluble in water & very slightly soluble or insoluble in most organic solvents, soluble in alkaline solution.

Identification(by HPLC)


The retention time of the major peak in the chromatogram of the sample solution corresponds to that in the chromatogram of standard solution, under the test for assay.
4. Water content (by KF) NMT 17.00 % w/w
5. Heavy metal NMT 10.0ppm
6. Calcium on anhydrous basis 07.00 % – 08.50 % w/w
7. Purity (As methyltetrahydrofolate)

(by HPLC)

NLT 95.00 %
8. Assay (As methyltetrahydrofolate) (by HPLC) NLT 95 % w/w (OAB)
9. Total plate count (CFU/g) NMT 1000 cfu /g
10. Yeast & Molds (CFU/g) NMT 100 cfu /g
11. E. coli. Absent/gm.
12. Salmonella Absent/10gm.


Category Description
Pharmaceutical & drugs

It is used to treat Depression, Megaloblastic Anemia, and Renal & Hepatic impairment. L-methylfolate is not an antidepressant or anti-psychotic medication. However, l-methylfolate may enhance the effects of antidepressant medications.

It is also used to treat Folate deficiency in people with major Depressive disorder.


L Methyl Folate is a B Vitamin (B9), which is used as a supplement for humans that triggers body's powerful anti-oxidants, glutathione, enhances the body's methylation and supports the cardiovascular system.

Additional Information

Additional Information.

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